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Abiraterone Price usa  is a non-steroidal drug with an antitumor antiandrogenic effect, used in the combined treatment of metastatic castration-resistant prostate cancer. tablets: oval biconvex, from white to almost white, engraved „AA250″ (in a cardboard box 1 bottle of 120 tablets); film-coated tablets: oval biconvex, brownish-pink, on one side with an engraving „AA“, on the other side – „500″ (in a cardboard box 5 blisters of 6 or 12 tablets). Abiraterone 250 mg (Zytiga) acetate – the active substance of Zytigi, is transformed into Abiraterone 250 mg (Zytiga), which is an inhibitor of androgen synthesis.Abiraterone Cost , in particular, selectively inhibits the activity of the enzyme CYP17 (17a-hydroxylase / C17,20-lyase), which is expressed and is required for androgen biosynthesis in the adrenal glands, testes and prostate tumor cells. CYP17 catalyzes the transformation of progesterone and pregnenolone by 17a-hydroxylation and cleavage of the C 17.20 bond to dehydroepiandrosterone and androstenedione (respectively), which are testosterone precursors. Also, against the background of inhibition of CYP17 activity in the adrenal glands, the biosynthesis of mineralocorticoids is enhanced. Androgen-sensitive prostate cancer responds to androgen-lowering therapy. Thanks to antiandrogenic therapy (for example, orchiectomy or the use of gonadotropin-releasing hormone agonists – luliberin), androgen biosynthesis is weakened in the testes. However, it does not affect the synthesis of androgens in the adrenal glands and in the tumor.
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